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    Archived pages: 58 . Archive date: 2013-08.

  • Title: QResearch - Home
    Descriptive info: .. Please enable scripts and reload this page.. If your browser does not support script, then you can visit the minimal version of this site at.. http://www.. qresearch.. org?Mobile=1.. Turn on more accessible mode.. Turn off more accessible mode.. Skip Ribbon Commands.. Skip to main content.. Go To QWeb.. |.. Sign Out.. Sign In.. To navigate through the Ribbon, use standard browser navigation keys.. To skip between groups, use SHIFT+LEFT or SHIFT+RIGHT.. To jump to the first Ribbon tab use CONTROL+[.. To jump to the last selected command use CONTROL+].. Site Actions.. This page location is:.. QResearch.. Home.. Browse.. Tab 1 of 3.. Page.. Tab 2 of 3.. Publish.. Tab 3 of 3.. "Generating new knowledge to improve patient care".. QRESEARCH specialises in research analyses.. using primary care electronic health data.. This Site.. Currently selected..  ...   QFeedback.. OpenPseudonymiser.. QInnovation.. Links.. Nottingham University.. EMIS.. EMIS NUG.. All Site Content.. specialises in research.. analyses using primary care.. electronic health data.. false,false,1.. Copyright © 2002-2012 University of Nottingham®.. ALL RIGHTS RESERVED.. Materials on this web site are protected by copyright law.. Access to the materials on this web site for the sole purpose of personal educational and research use only.. Where appropriate a single print out of a reasonable proportion of these materials may be made for personal education, research and private study.. Materials should not be further copied, photocopied or reproduced, or distributed in electronic form.. Any use or distribution for commercial purposes is expressly forbidden.. Any other use or distribution of the materials, particularly of a commercial nature, may constitute an infringement of the University's copyright and may lead to legal action..

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  • Title: QResearch - What Is QResearch
    Descriptive info: What Is QResearch.. What Is QResearch.. What is QRESEARCH?.. QRESEARCH is a large consolidated database derived from the anonymised health records of over 13 million patients.. The data currently come from 660 general practices using the EMIS clinical computer system.. The practices are spread throughout the UK and include data from patients who are currently registered with the practices as well as historical patients who may have died or left.. Historical records extend back to the early 1990's making it one of the largest and richest general practice databases in the world.. The aim.. To develop and maintain a high quality database of general practice derived data for use in ethical medical  ...   The researchers will be provided with patient or practice level data that is required to answer their research question - not the whole dataset.. The costs of use of the data will be carefully controlled to allow the scheme to be self-funding but to allow good access to academic researchers.. Analyses are undertaken to demonstrate the accuracy and completeness of the data and are available for morbidity analyses.. The entire database has been linked to cause of death data at individual pateint level with linkages extending back as far as 1993.. Approval has now been given by the National Information Givernance Board, to link QResearch to cancer registries and hospital episode statistics..

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  • Title: QResearch - Organisation
    Descriptive info: Organisation.. QRESEARCH.. is not for profit organisation which is jointly owned by the University of Nottingham and EMIS (the leading IT supplier for computer systems in primary care).. Strategic decisions are be taken by a.. Management Board.. representing the interests of EMIS and the University of Nottingham.. An.. Advisory Board.. sets policy and oversees the operation and governance of the database.. A.. Scientific Committee.. approves access to data.. is housed within the Division of Primary Care, University of Nottingham..

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  • Title: QResearch - Confidentiality
    Descriptive info: Confidentiality.. QRESEARCH has extensive, robust protection of confidentiality for patients and the practices.. Key features.. No patient identifiers are extracted from the practices.. Patients are pseudo-anonymised to protect their identity but allow their records to be updated.. Researchers only receive anonymised data.. Special protection is employed to protect practice identity.. The two QRESEARCH servers are in secure environments.. Data transfers are encrypted.. Use of the data is strictly controlled.. QRESEARCH is Section 60 compliant and has approval from the Trent Multi-Centre Research Ethics Committee.. Pseudo-anonymised data.. No data is extracted from a practice database that contains any strong patient identifier, such as name, address, full postcode, date of birth etc.. The practice computer allocates a unique number to each patient (a GUID).. This GUID is used by the practice system to allocate later data to the same patient file.. The collection server cannot identify which patient the GUID refers to.. As an additional protection, this GUID is further encrypted at the point of collection by the collection server using a hash key that the collection server maintenance personnel do not have access to.. This additional protection prevents the potential for the GUID from the research database being taken back to the practice, the database being illegally accessed and the GUID cross referenced back to the patient.. This process of anonymisation is much stronger than the MIQUEST identifiers.. Similarly, each practice is also allocated a unique code but no practice identifiers are retained.. In the national phase, when the data are fully pseudo-anonymised, no-one (including EMIS) can track back to the practice of origin from the resulting database.. Anonymised data.. Researchers, having gone through the process of approval, are given, if appropriate, files that contain records for individual patients.. However these records do not contain a GUID and are therefore truly anonymised.. When the database is interrogated for information for morbidity studies etc, the results do not contain any records for individual patients.. The outputs are in tables, graphs etc and we refer to these as tabular analyses.. Protection for practice identity.. One named member of staff in Nottingham and one in EMIS have a list of the practices that have given and returned signed consent to participate in QRESEARCH during recruitment.. This list is kept on a separate computer from the EMIS file server or the research server in Nottingham; and is encrypted.. The list of participating practices will not be released to other individuals or organisations by EMIS or Nottingham.. There  ...   to give fully informed consent and enter the data themselves onto a template within their surgery system.. QRESEARCH servers.. There are several servers involved in the QRESEARCH project.. (a) The data collection server at EMIS.. This server is linked to practices via the NHSnet in order to undertake the triggered upload ONLY after the practice has authorised the upload by activating the QRESEARCH module within its surgery system.. (b) The research server, which houses the resulting aggregated database, and which is located at The University of Nottingham.. The research computer is a stand-alone computer (i.. e.. it is not linked to the NHSnet or internal or external networks).. This computer is the single point of access to the data collected by QRESEARCH.. Each of the servers (at EMIS and at Nottingham) are used solely for the purposes of QRESEARCH.. Data transfers.. EMIS only transfers QRESEARCH data to The University of Nottingham.. The data transfer will be secure as the data are encrypted.. Use of the data.. EMIS and The University of Nottingham are contractually bound not to use the data collected by QRESEARCH for any other purpose than QRESEARCH.. Access by researchers is carefully regulated since they will receive patient level sub-sets of the database.. See Using it for Research.. Morbidity analyses will be undertaken as appropriate - see.. Using it for data analyses.. The results will be included on the website - see.. Current data analyses.. Section 60 compliance.. In order to clarify whether Section 60 support was necessary to cover the process of anonymisation/pseudo-anonymisation, we contacted Sean Kirwan from the Department of Health with a copy of the protocol and details of the processes to be used.. He advised us that Section 60 support was necessary only when patient identifiable information is required and it is not practicable to either obtain patient consent or use anonymised/pseudonymised data.. With the process of pseudo-anonymisation employed in QRESEARCH, no patient identifiable information will be shared with, or processed by, a third party (ie an individual or organisation not employed by the GP practice) and hence Section 60 support is not required for the QRESEARCH database.. Multi-Centre Research Ethics Committee.. QRESEARCH has full approval from the Trent MREC [Ref: MREC 03/04/021].. Research studies which utilise QRESEARCH data need to obtain ethical approval from this committee.. The contact for the MREC administrator is:.. Ms Jill Marshall.. Trent MREC.. Derwent Shared Services.. 6th Floor Laurie House.. Colyear Street.. Derby.. Derbyshire.. DE1 1LJ.. Email:.. Jill.. Marshall@DerwentSharedServices.. nhs.. uk..

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  • Title: QResearch - ContactUs
    Descriptive info: ContactUs.. ContactUs.. Contact us.. Professor Julia Hippisley-Cox.. julia.. hippisley-cox@nottingham.. ac.. The Division of Primary Care.. 13th Floor.. Tower Building.. University of Nottingham.. NG7 2RD.. [.. Map of how to find us.. ]..

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  • Title: QResearch - Information for researchers
    Descriptive info: Information for researchers.. Information for Researchers.. The QRESEARCH Advisory Group draws up the criteria for access that are applied by the QRESEARCH Scientific Committee.. Researchers wishing to use the data should build in plenty of time into their schedule since it takes time to process applications and prepare data sets.. Researchers will need to do as much work to help define their search criteria as possible and we are developing web tools to help with this.. Researchers will, however, need to enlist clinical GP support in their institution to help define case definition for their searches.. QRESEARCH releases data to academics employed by UK universities to undertake bone fide research.. We assess eligibility of applications using the following questions.. Did you have the original idea for this research project?.. To your knowledge is this work original and capable of publication as original research in a peer- reviewed journal?.. Are you free to undertake this study and publish its findings without needing to clear it with the funding source or any other organisation?.. Do you agree to acknowledge the source of QRESEARCH data in any publication, paper or report?.. Do you agree NOT to attempt to identify patient(s) or practice(s)?.. Do you undertake to provide a copy of the final report of the project and copies of any publications within one year of the project completion?.. Do you agree NOT to release the data to any third party including the funder, sponsor or other such body?.. Do you agree not to use the data for any other project except that which is expressly described in your protocol.. Do you undertake to check the data you are given within a month of receipt and report back any problems within that time?.. Do you have a statistician on the project team who has contributed to the design of the study and will advise on the analysis?.. An answer of ‘no’ to any of the questions is likely to invalidate the application.. If you are an academic employed by a UK university, please read the following information and also look at the publications page for examples of studies which have been undertaken.. How does it work?.. Researchers originate a research question or hypothesis; write an outline protocol; and contact QRESEARCH to discuss the feasibility of undertaking the study.. If the study is feasible, QRESEARCH will give an broad estimate of the costs of providing the data and will provide a letter to accompany any application for funding.. The researcher then secures the necessary funding and completes the QRESEARCH application form, including a detailed protocol and data specification.. This application is sent for scientific review and feedback is given to the researcher.. The researcher makes any necessary modifications to the protocol and approval is obtained, the researcher is given a timescale for the data extraction.. Once the researcher has the data, they have to approve it within one month of receipt.. How much does it cost?.. QRESEARCH is not-for-profit and is entirely self-funding so needs to cover the costs associated with providing a research service.. We will estimate the cost of each data extraction plus VAT.. The estimate will take account of the complexity of the data required and the time taken to extract it.. If the specification becomes more complex, then the cost will be uplifted.. QRESEARCH will submit an invoice to the Principal Investigator for the work concerned.. This will be paid in advance of the data being extracted.. Who is eligible to apply for research access?.. QRESEARCH was established specifically to provide access for research projects by academics employed by UK universities.. A license agreement will be between QRESEARCH and the employing University.. At least on member of the research team must be a medically qualified academic registered with the General Medical Council who signs the guarantee.. What types of studies are most suitable?.. We will provide extracts of data on samples of patients with sufficient data to be able to test the hypothesis.. The sample size will depend on the sample size calculation.. We do not license the use of the whole database.. Any research analyses which might involve the whole database or which need a practice level analysis need to be done on site and are subject to QRESEARCH having adequate capacity.. The following studies are most suitable:.. Case control studies designed to examine risk factors for onset of disease.. Cross sectional surveys.. Cohort studies.. Sample size calculations.. Are there studies which cant be done on QRESEARCH?.. Yes, there are some types of studies which are not suitable for QRESEARCH.. The QRESEARCH team will let researchers know at an early stage if a study is not suitable.. In particular, QRESEARCH cannot undertake studies which involve:.. any intervention on practices or patients.. any need to contact the practices or patients since this is impossible.. any changes to the fundamental principles underpinning QRESEARCH.. data which is not already held by QRESEARCH.. Are there any data items which are not released?.. In order to safeguard the identity of the practices, we do not release any practice level data or any individual Townsend Score.. We also make special consideration of data items relating to patients with very rare or  ...   the project.. This can be for a variety of reasons including a failure to identify the necessary funds.. Our Scientific Board is unpaid and so we only ask them to review projects which are almost certainly going ahead.. We ask the Scientific Board to review them before the MREC to ensure that the protocol which then goes to MREC doesn’t need to be amended and hence re-submitted.. I just want all the data for the patients of interest.. Is this OK?.. No.. We expect researchers to have a specific research question/hypothesis that requires specific data.. We do not license the whole database or give out entire medical records.. The maximum number of patients which can be supplied is 100,000 and will usually be less than this.. What do I need to do if my research question changes?.. The approval you gain is on the basis of the protocol submitted to the Scientific Board.. If you would like to answer another research question which is not in your original protocol then you must re-submit it as a new project for peer review.. An additional charge is likely since data are licensed on a per study basis.. What happens if my research team changes or I move institutions?.. QRESEARCH data may onluy be accessed by individuals and organisations and.. for the purposes of the research which has been approved.. You may not transfer, distribute, share, sell or sublicense the data to any third party.. Specifically, you may not transfer the data outside the UK.. Shuld there be any changes in the individuals or organisations undertaking the research, you must notify QRESEARCH so that an amended data agreement can be negotiated.. What if I don’t want to do the research but I want to know the answer?.. QRESEARCH may also do commissioned research if appropriate.. This can be done in collaboration or as a service for which QRESEARCH will give a formal quote.. QRESEARCH has a standard draft contract for this type of work which is available on request.. Is there an appeal process if my application to QRESEARCH is not approved?.. Reasons for refusal for an application include failure to comply with the essential criteria noted above or because the application fails to pass the scientific review process.. It could also include failure by the applicants to produce academic papers from previous studies where QRESEARCH data has been supplier.. Should an application be rejected, the applicant is welcome to make the appropirate changes and submit a new application which would be expected to be substantially different to the original one.. A covering letter documenting the reason for the appeal, what reasons had been given by QRESEARCH for the rejection, what actions and amendments had been undertaken.. A charge for processing the application may be raised to cover the cost of administering the appeal.. What happens if there is a mistake in the data?.. QRESEARCH will take every precaution to ensure that the data requested match the exact specification which has been agreed and signed off by the principal investigator.. The data extraction process will be subject to routine quality assurance procedures.. It is the principal investigator’s responsibility to confirm receipt of the data and check the data and notify QRESEARCH of any errors or omissions within 28 days.. In the absence of any such notification we shall consider that the data are correct.. If there is a mistake in the data, then the principal investigator should contact QRESEARCH.. who will investigate the problem.. If there is a mistake in the data extraction caused by QRESEARCH error, then the principal investigator will be provided with a corrected dataset within 28 days or as soon as is reasonably possible.. QRESEARCH cannot be liable for the cost of any staff time spent working on the data.. If the mistake is due to an error in the data specification drawn up by the researchers (eg the researchers have selected the wrong Read codes), then QRESEARCH will endeavour to help by re-running the data extraction routine with the new codes within the following 3 months.. There will be an additional cost for this.. Publication of results.. The results of all studies using QRESEARCH data must be published and the results must be publically available to maximise the public benefit but also to reduce the risk of publication bias.. The underlying individual level data for the paper must not be shared under any circumstances.. Requests to access the individual level data must be directed to QRESEARCH who will consider the request as a new application.. Researchers must consider the risk of identifying individuals in their analysis prior to publication and must not publish small numbers (which are counts 1-5).. A higher level of aggregation should be considered when analyses produce less than 5 cases.. How long do I have to undertake my research?.. We will write to you after two years to invite you to submit for an extension to continue to use the data or to ask you to destroy the data if the project has finished and provide a report on the study.. QRESEARCH Scientific peer review.. (PDF).. QRESEARCH Scientific peer review.. (Word).. QRESEARCH Data License Template.. Application Form.. Application Form..

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  • Title: QResearch - Information for practices
    Descriptive info: Information for practices.. Practice information sheet.. Background.. In 2003, the University of Nottingham and EMIS established a new high quality ethical database for research known as QRESEARCH.. This database, which is now the largest of its kind worldwide, consists of the anonymised records of over 13 million patients who have been registered with over 660 practices spread throughout the UK.. Results of research undertaken using QRESEARCH are all published and can be found at.. org.. We have many examples of projects which have helped inform health care policy or enrich understanding of the causes and outcomes from diseases and their treatments.. Click here.. to see an overview of QResearch and related projects.. Why is QRESEARCH wanting to expand?.. We want to expand the size of QRESEARCH in order to.. get better coverage of some parts of the UK (we need at least three practices in a geographical area in order to be able to report at that level).. increase to increase the number of practices with longitudinal data tracking back over a decade to enable us to develop new risk prediction algorithms such as QRISK (new CVD risk score developed - see http:\\www.. qrisk.. org).. which can be integrated back into the clinical system.. enhance our ability to undertake research on rare diseases.. to enable the rapid evaluation of the safety and effectiveness of newly introduced medication.. Why has my practice been invited to participate?.. We are inviting all practices using EMIS clinical systems (EMIS Web or LV) to take part.. Does the practice have to take part?.. It is entirely up to the practice as to whether they wish to take part.. Practices who agree to take part will activate QRESEARCH within their surgery system.. The practice will only be included in the project once this activation has been done.. What will happen if the practice takes part in QRESEARCH ?.. GP computer systems are currently connected to EMIS via the NHSNet for support and patching of system upgrades.. EMIS will use this link to first upload key census related variables such as the deprivation score (called the Townsend Score) and a marker of rurality.. into the patient’s electronic record.. These data items will be stored in the patients’ record but will not be available on the patient’s registration screen.. The scores are derived from the national census and are linked to the electoral ward or output areat in which the patient lives.. The scores are used in research to measure or monitor uptake and provision of health services.. The practice system will then generate an upload of the pseudoymised data and transmit this data via the N3 network to a dedicated server within EMIS.. The data are pseudonymised with a 'one way' hashing algorithm which cannot be reversed theereby protecting patient confidentiality.. he data are updated on a daily basis and this update does not interfere with the running of the practice or any back-ups.. EMIS undertakes a secure transmission of the aggregated data to the University of Nottingham.. To ensure maximum security, the data are encrypted and will be stored on a very secure server in the University of Nottingham.. Physical access to the database is very restricted.. The University of Nottingham is the only point of access to the data.. What data is uploaded?.. QResearch only uploads pseudonymised coded data: year of birth, sex, registration dates, deprivation score, ethnicity, referrals, consultatinos, prescriptions, clinical values (eg blood pressure), test results and clinical events such as diagnoses.. Dates of birth are rounded to year of birth.. No free text or strong patient identifiers are uploaded.. Patients are excluded from the uploads if they have a read code indicating they have rfused consent (Read code 93C1 or 93C3).. Any items marked as confidential by the GP are also excluded from the uploads.. How does the data linkage work?.. The QResearch database is be linked to other sources of data such as cancer registries, deaths data and hospital episode statistics.. This information is linked to Qresearch using the same pseudonymisation process which is applied to the NHS number in the secondary daa source before the data is released to the University of Nottingham.. The data is then be linked on the pseudonymn without the need for disclosure of any strong identifiers to QResearch.. How do I activate QRESEARCH?.. Please email.. for instructions quoting your CDB number.. You can check the activation status in LV by selection ST - IS.. There will  ...   in QRESEARCH and to gain and retain the respect of the public, the NHS, practices and the research community.. Its membership will include representatives of the following organisations:.. The Royal College of General Practitioners.. The British Medical Association itself and its General Practitioners Committee.. EMIS National Users Group.. A representative of the practices contributing data to QRESEARCH.. EMIS.. T.. wo patient representatives.. University.. of Nottingham.. Chair of the Scientific Committee.. What are the requirements for the projects undertaken using QRESEARCH?.. There are two types of projects that will use QRESEARCH.. The first type will be research projects and many of these will require a subset of QRESEARCH to analyse.. Research projects undertaken using the QRESEARCH data will fulfil the following criteria.. (a).. They have a named principal investigator and named co-investigators (at least one co-investigator will have an academic track record).. (b).. They will have a written protocol with a clear research question.. (c).. They will have current ethical committee approval for the project.. (d).. They will have a research sponsor and will meet the requirements of research governance.. (e).. They will agree to acknowledge the source of data in any publication or report (which will never identify any individual practices).. (f).. They will guarantee their academic independence, including their ability to publish their findings regardless of the implications for any sponsor or funder.. (g).. The QRESEARCH Scientific Committee will need to give approval within the guidelines set out by the QRESEARCH Advisory Board before any analysis can occur and before the data can be supplied to the user.. The second type of project will require tables of data.. These morbidity surveys will not require the release of a subset containing patient level data, but just analyses.. The results of these analyses will be placed on the QRESEARCH website (www.. Applicants for tabular data will need to be approved by the Advisory Board.. Under no circumstances will QRESEARCH data made available to pharmaceutical companies for post marketing surveillance.. There may be circumstances in which is it may be in the public interest to undertake analyses of.. safety for new and commonly used medications and in these special circumstances it may be necessary for QRESEARCH to have contact with the pharmaceutical industry via a third party such as the MHRA or the MRC/Wellcome.. For example, in a flu pandemic situation we may need to rapidly assess whether a newly developed flu vaccine is likely to be safe and effective.. As with any research project however, will be undertaken by a researcher who can guarantee academic independence in design and analysis as well as freedom to publish in according with our governance framework.. All studies will be approved by the Scientific Board and notified to the Advisory Board.. The protocol for the studies will be publically available as will any information on.. funding to support this activity.. Practices who wish to be in QRESEARCH but not allow their data to be used for dug safety studies will be able to indicate this and their data will not be used for this purpose.. Will the identity of practices taking part in QRESEARCH be kept confidential?.. Yes, the participation of the practice in QRESEARCH will be confidential.. The Advisory Board, let alone any users of the QRESEARCH data will not know the identity of the practice.. The practice will not be named in any report or publication.. What happens to the results of the research projects?.. All projects undertaken using QRESEARCH are to be made publically available without charge.. We expect researchers who use QRESEARCH data for their research to publish the findings in peer reviewed journals.. We will keep a list of all publications which is available on.. Who is organising the research and who are the guarantors?.. QRESEARCH is a joint venture between the Univeristy of Nottingham and EMIS.. The project is organised and guaranteed by Professor Julia Hippisley-Cox, GP and professor of General Practice (University of Nottingham) and Dr Shaun O'Hanlon (Clinical and Development Director, EMIS).. Contact details:.. E-mail: julia.. uk.. Further queries.. If you have any queries about QRESEARCH, then please contact professor Julia Hippisley-Cox email.. Further details about QRESEARCH including the full protocol and documentation can be found on the QRESEARCH website (www.. If you have any complaints about the way that QRESEARCH is being conducted, please contact:.. Dr Chris Frith.. EMIS National User Group, Suite 15, Enterprise House, Kingsway North, Team Valley, Gateshead, Tyne Wear.. NE11 0SR.. hfdgp@aol.. com..

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  • Title: QResearch - InstructionsToActivate
    Descriptive info: InstructionsToActivate.. InstructionsToActivate.. Instructions to activate QResearch.. If you wish to activate Qresearch please email.. and quote your CDB number..

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  • Title: QResearch - Information for patients
    Descriptive info: Information for patients.. Information for Patients.. Q:.. What is QRESEARCH ?.. A:.. QRESEARCH is an organisation that takes data from your GPs computer system, sorts it, links it to other centrally held medical information, then makes the information available to medical researchers.. What sort of information is taken from the GPs computer system?.. Unrecognisable information is taken from the GPs system about the illnesses people have had and what treatment the doctor gave them.. What is this information used for?.. This information is used to compare many different types of treatment to see what is the most effective.. It is also used to try and discover if, for example, having one type of illness makes people more likely to get another type of illness.. Who supplies this information?.. This information is supplied by over 680 GP practices and the system has over 13 million records.. Exactly what information is sent to QRESEARCH?.. Only medical information is sent.. No personal details about you are ever  ...   to researchers?.. The information is given to approved researchers in the form of tables.. No personal information (your name, address etc.. ) cannot be given to the researchers because QRESEARCH does not have this information.. Who runs QRESEARCH?.. QRESEARCH is managed by the Chief Executive of EMIS – the company who supplies your GP with their computers – and a Professor of General Practice at Nottingham University.. QRESEARCH has an Advisory Board - who ensure that it is run correctly and ethically – of medical professionals and two patient representatives.. Does anyone profit financially from the use of my information?.. Apart from the computer technicians who are paid by Nottingham University, no one is paid for their role in QRESEARCH.. QResearch reimburses reasonable expenses for members of its advisory board, covering cost of travel and attendance at meetings.. Further, more detailed information on QRESEARCH and the results of research projects can be obtained from our website:.. www.. Terence Wiseman.. Patient Representative,.. QResearch Advisory Board..

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  • Title: QResearch - Publications
    Descriptive info: Publications.. We aim to publish all our work.. Here are our research papers and reports using QRESEARCH and related data sources:.. Papers published in peer-reviewed journals.. Conference abstracts in peer-reviewed journals.. Reports.. (and other papers)..

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  • Title: QResearch - Conference Proceedings
    Descriptive info: Conference Proceedings.. Conference Proceedings.. Exposure to bisphosphonates and risk of gastrointestinal cancers: series of nested case-control studies using QResearch data.. Yana Vinogradova.. Abstract accepted for oral presentation at the 41st Annual Scientific Meeting of the SAPC, SECC, Glasgow, 2-4th October 2012.. A reference standard for evaluating methods for drug safety signal detection using Electronic Healthcare Records (EHR) Databases.. Coloma PM, Avillach P, Schuemie MJ, Ferrajolo C, Ottosson A, van der Lei J, Sturkenboom M, Trifiro G on behalf of the EU-ADR Consortium.. Presented at the 11th Annual Meeting of the International Society of Pharmacovigilance, 26-28 October 2011, Turkey (Abstract OP05).. Electronic Healthcare Records (EHR) Databases for Drug Safety Signal Detection: What can we expect?.. Coloma PM, Trifirò G, Schuemie MJ, Gini R, Herings R, Hippisley-Cox J, Mazzaglia G, Picelli G, Corrao G, Pedersen L, van der Lei J, Sturkenboom M on behalf of the EU-ADR Consortium.. In: Proceedings of the 11th Annual Meeting of the International Society of Pharmacovigilance, 26-28 October 2011, Turkey (Poster Abstract PP032).. Drug use and acute liver injury in children: signal detection using multiple healthcare databases.. Ferrajola C, Trifirò G, Coloma PM, Schuemie MJ, Gini R, Herings R, Hippisley-Cox J, Mazzaglia G, Picelli G, Scotti L, Pedersen L, van der Lei J, Sturkenboom M on behalf of the EU-ADR consortium.. Abstract submitted to the 11th Annual Meeting of the International Society of Pharmacovigilance, 26-28 October 2011, Turkey (Poster Abstract PP167).. Comparison of Signal Detection through Healthcare Database Network vs.. Spontaneous Reporting System Database: the EU-ADR experience.. Trifiro G, Patadia V, Coloma PM, Schuemie MJ, Gini R, Herings R, Hippisley-Cox J, Mazzaglia G, Picelli G, Scotti L, Pedersen L, Avillach P, Van Der Lei J, Sturkenboom M, on behalf of the EU-ADR group.. In: Proceedings of the 11th Annual Meeting of the International Society of Pharmacovigilance, 26-28 October 2011, Turkey (Poster abstract PP181).. For how many and what types of drugs can longitudinal healthcare databases detect safety signals? A view from the EU-ADR Project.. Coloma PM, Trifirò G, Schuemie MJ, Gini R, Herings R, Hippisley-Cox J, Mazzaglia G, Gino Picelli G, Corrao G, Pedersen L, van der Lei J, Sturkenboom M on behalf of the EU-ADR consortium.. Poster for presentation at the present at the International Conference on Pharmacology and Therapeutics, 14-17 August Chicago, Illinois, USA.. Harmonization of the event identification process in eight European healthcare databases: the experience from the EU-ADR project.. Trifirò G, Avillach P, Gini R, Coloma PM, Mazzaglia G, Picelli G, Scotti L, Herings R, Hippisley-Cox J, Molokhia M, Pedersen L, Fourrier-Réglat A, Pariente A, Sturkenboom M, van der Lei J on behalf of the EU-ADR consortium.. Abstract accepted for oral presentation at the 27th International Conference on Pharmacoepidemiology Therapeutic Risk Management (ISPE), 14-17 August 2011, Chicago, Illinois, USA.. Exposure to Cyclo-Oxygenase-2 inhibitors and risk of Cancer: Nested Case-control Studies.. Vinogradova Y, Coupland C, Hippisley-Cox J.. IEA World Congress of Epidemiology, 7-11 August 2011, Edinburgh International Conference Centre, Edinburgh [.. PowerPoint presentation.. ].. Exposure to cyclo-oxygenase-2 inhibitors and risk of cancer:.. nested case-control studies.. IEA World Congress of Epidemiology, Edinburgh, 7-11 August 2011 (Accepted for oral presentation).. EU-ADR healthcare database network vs.. spontaneous reporting system database: preliminary comparison of signal detection.. Trifiro G, Patadia V, Schuemie MJ, Coloma PM, Gini R, Herings R, Hippisley-Cox J, Mazzaglia G, Giaquinto C, Scotti L, Pedersen L, Avillach P, Sturkenboom MCJM, Van Der Lei J, on behalf of the EU-ADR group.. In: Proceedings of the Second International Patient Safety through Intrelligent Procedures in medication (PSIP) Workshop, Paris, 6-17th May 2011.. Is low-dose aspirin use associated with a reduced risk of colorectal cancer? A QResearch primary care database analysis.. Logan RF, Vinogradova Y, Coupland CA, Hippisley-Cox J.. Oral Presentation at the British Society of Gastroenterology Annual Meeting, International Convention Centre, Birmingham, 14-17 March 2011).. Harmonising definitions of adverse events among 8 European healthcare databases participating in the EU-ADR project.. Gini R, Avillach P, Coloma PM, Mougin F, Dufour J, Thiessard F, Joubert M, Mazzaglia G, Giaquinto C, Fornari C, Herings R, Hippisley-cox J, Molokhia M, Pedersen L, Fourrier-réglat A, Fieschi M, Sturkenboom M, Van Der Lei J, Pariente A, Trifirò G.. EuroEPI 2010 Epidemiology and public health in an evolving Europe; Florence, Italy, 6-9 November 2010 (Abstract code 1211).. Continuing Undue Risks in UK Prescribing of Non-Steroidal Anti-Inflammatory Drugs.. Vinogradova Y, Leighton M, Hippisley-Cox J, Hawkey CJ.. In: Proceedings of Digestive Disease Week, 1-5 May 2010, New Orleans.. Exposure to statins and risk of common cancers: a series of nested case-control studies.. Accepted for presentation at the  ...   Agency.. Patients at high risk of pneumonia: population case-control study (Oral Presentation, Abstract number: 1073).. Vinogradova Y, Hippisley-Cox J.. 37th Annual Scientific Meeting of the SAPC, 9-11 July 2008, National University of Ireland, Galway.. How will English STI Surveillance Be Improved By Supplementing Routine GUM Data with Data from General Practice?.. Yung M, Hughes G, Cassell J, Mercer C, Smith G, Harcourt S.. Annual Spring BASHH conference, 2008.. In: Proceedings of the Royal College of General Practitioners, Annual Conference, 2008.. Primary Care Surveillance in the UK: Action, Outcomes, Benefits (Oral presentation).. Cooper DL, Smith GE, Elliott D, Harcourt S, Loveridge P, Smith S, Ibbotson S, George R, Hippisley-Cox J.. Advances in Disease Surveillance 2007; 2: 100.. Inequalities in uptake of influenza vaccine by deprivation and risk group: time trend analysi.. s.. Coupland C, Harcourt S, Vinogradova Y, Smith G, Joseph CA, Pringle M, Hippisley-Cox J.. International Meeting of Epidemiology, Dublin, 2007.. Using electronic health record (EHR) networks for large-scale studies on quality of care.. Gill JM, Ornstein S, Carney P, Hippisley-Cox J.. Proceedings of the 36th NAPCRG Annual Meeting; North American Primary Care Research Group, Vancouver, 20-23 October, 2007.. Do Statins Affect Risk of Pneumonia in the General Population: Nested Case Control Study.. Vinogradova Y, Hippisley-Cox, J.. In: Proceedings of the 36th NAPCRG Annual Meeting; North American Primary Care Research Group, Vancouver, 20-23 October 2007.. Quality and Outcomes Time Trends Analysis in QRESEARCH 2001 to 2006.. Hippisley-Cox J, Vinogradova V, Coupland C.. In: Proceedings of the Society for Academic Primary Care, 36th Annual Scientific Meeting, London, July 2007.. Pandemic Quality Surveillance: How the UK is preparing for daily health information during a flu pandemic?.. Joseph CA, Noakes KL, Mook P, Desai S, Gates P, Smith G, Hippisley-Cox J, Edmunds J, Watson J.. In: Proceedings of the International Influenza Meeting, Toronto, 17-23 July 2007.. Is gonorrhoea under control in England.. Hughes G, Leong G, Ward H, Hippisley-Cox J, Ison C.. International Society for Sexually Transmitted Diseases Research, Seattle, 2007.. Risk of colorectal cancer in patients taking Statins and non-steroidal anti-inflammatory medication: nested case control study.. Vinogradova Y, Hippisley-Cox J, Coupland C, Logan R.. In: Proceedings of the 14th United European Gastroenterology Week, Berlin, Germany, 21-25 October 2006.. Risk of colorectal cancer in patients taking statins and non-steroidal anti-inflammatory medication: nested case control study.. In: Proceedings of the 35th NAPCRG Annual Meeting; North American Primary Care Research Group, Tuscon, Arizona, USA.. 15 -18 October 2006.. Influenza vaccine uptake in the UK, an analysis by underlying disease risk group and socio-demographic factors.. Harcourt SE, Coupland C, Vinogradova Y, Smith GE, Joseph CA, Pringle M, Hippisley-Cox J.. In: Proceedings 4th Annual Conference, Health Protection Agency; Health Protection 2006; University of Warwick, 11-13 September 2006.. Primary Care Surveillance – Are we bovvered?.. Smith G, Cooper D, Elliott A, Harcourt S, Hippisley-Cox J, Loveridge P, Smith S, Ibbotson S, George, R.. In: Proceedings of the 4th Annual Conference of the Health Protection Agency; University of Warwick, Poster Presentation, 11-13 September 2006.. The new QFLU daily analysis service supporting influenza pandemic planning.. Porter, A, Hippisley-Cox, J, Smith GE, Harcourt, SE, Stables, D, Charlett, A, Painter, MJ.. In: Proceedings of the 4th Annual Conference, Health Protection Agency; Health Protection 2006; University of Warwick, 11-13 September 2006.. Risk of malignancy in patients with mental health problems (Parallel 037).. Vinogradova Y, Hippisley-Cox J, Coupland C, Parker C.. In: Proceedings of the Society for Academic Primary Care, 35th Annual Scientific Meeting; The contribution of research and education to patient-centred primary care.. 12-14 July 2006, Keele University.. Description of a collaborative project to prove timely primary care derived data for health protection surveillance at SHA level across the UK.. Harcourt SE, Smith GE, Hippisley-Cox J, Pringle M, Heaps M, Langford G, Porter A, Charlett A, Pebody R, Painter MJ.. In: Proceedings of the Five Nations Health Protection Conference, May 2006, Cardiff City Hall.. Report of the first year of a pilot, national, primary care surveillance project.. Harcourt SE, Smith GE, Hippisley-Cox J, Pringle M, Langford G, Nicoll A, Charlett A, Painter MJ.. In: Proceedings of the Health Protection Agency Conference September 2005, University of Warwick (Abstract P119).. What’s happening in my SHA? Use of a recently developed national GP database for health protection surveillance.. Smith GE, Harcourt SE, Hippisley-Cox J, Pringle M, Nicoll A, Painter MJ.. In: Proceedings of the Health Protection Agency Conference September 2004, University of Warwick (Abstract P54).. How representative are Trent Focus Research Practices?.. 1st Annual Conference of the UK Federation of Primary Care Research Networks 1998..

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